DORI VOSITALARINING NOJO‘YA TA'SIRLARINI NAZORAT QILISHNING ZAMONAVIY USULLARI
Abstract
Dori vositalarining nojo‘ya ta'sirlari (adverse drug reactions – ADR) zamonaviy sog‘liqni saqlash tizimining eng dolzarb muammolaridan biri hisoblanadi. Jahon sog‘liqni saqlash tashkiloti ma'lumotlariga ko‘ra, nojo‘ya dori reaksiyalari kasallanish va o‘limning muhim sabablaridan biri bo‘lib qolmoqda. Mazkur maqolada farmakovigilans tizimining rivojlanishi, nojo‘ya ta'sirlarni aniqlash, baholash, monitoring qilish va oldini olishning zamonaviy usullari tahlil qilindi. Sun'iy intellekt, katta ma'lumotlar (Big Data), elektron tibbiy yozuvlar, farmakogenomika va real klinik amaliyot ma'lumotlaridan foydalanish imkoniyatlari yoritildi. Shuningdek, xalqaro tajriba va rivojlanayotgan davlatlarda farmakovigilans tizimini takomillashtirish istiqbollari ko‘rib chiqildi.
References
1. World Health Organization. Pharmacovigilance: Ensuring the Safe Use of Medicines.
2. Uppsala Monitoring Centre. WHO Programme for International Drug Monitoring.
3. European Medicines Agency. Guideline on Good Pharmacovigilance Practices.
4. U.S. Food and Drug Administration. FDA Adverse Event Reporting System.
5. Edwards I.R., Aronson J.K. Adverse Drug Reactions: Definitions, Diagnosis and Management.
6. Strom B.L. Pharmacoepidemiology.
7. Waller P. An Introduction to Pharmacovigilance.
8. Talbot J., Aronson J.K. Stephens' Detection and Evaluation of Adverse Drug Reactions.
9. Meyboom R.H.B. Pharmacovigilance and Drug Safety.
10. Hartigan-Go K. Global Perspectives on Drug Safety Monitoring.
