MAVRAK (SALVIA OFFICINALIS L.) NING FARMAKOLOGIK XOSSALARI
Abstract
Ushbu maqolada mavrak (Salvia officinalis L., Lamiaceae oilasi) o'simligining fitokimyoviy tarkibi, biologik faolligi hamda zamonaviy farmakologiya va integrativ tibbiyotdagi o'rni o'rganilgan. Tadqiqotimiz maqsadi — mavrakka oid 2020–2024 yillar orasida chop etilgan xalqaro ilmiy ishlarni tizimlashtirish va uning terapevtik salohiyatini kompleks baholashdan iborat. Ishda adabiyotlarni tahlil qilish, qiyosiy va tizimlashtirish metodlaridan foydalanildi. Natijalar shuni ko'rsatadiki, o'simlik tarkibidagi rozmarinova kislota, karnosik kislota, karnosol, flavonoidlar va efir moylari kuchli antioksidant, antimikrob, yallig'lanishga qarshi va neyroprotektiv ta'sir ko'rsatadi. Mavrak zamonaviy farmakologiyada, nevropsixiatriya va metabolik kasalliklarni davolashda istiqbolli dorivor o'simlik sifatida ilmiy jihatdan asoslanmoqda.
References
1. D. Garg and V. Kumar, "A Review of Therapeutic Properties and Uses of Salvia officinalis," Journal of Pharma Insights and Research, vol. 2, no. 3, pp. 146-154, 2024.
2. A. Yilmaz et al., "Bioactive chemical composition and pharmacological insights into Salvia species," Frontiers in Molecular Biosciences, vol. 12, p. 1678109, 2025.
3. I. N. Misharina et al., "Natural Compounds of Salvia L. Genus and Molecular Mechanism of Their Biological Activity," Molecules, vol. 28, no. 24, p. 8065, 2023.
4. H. M. Assaggaf, H. N. Mrabti, B. S. Rajab, A. A. Attar, and A. Bouyahya, "Chemical Analysis and Investigation of Biological Effects of Salvia officinalis Essential Oils at Three Phenological Stages," Molecules, vol. 27, no. 16, p. 5157, 2022.
5. H. A. Alomar, W. M. Elkady, M. M. Abdel-Aziz, T. A. Ibrahim, and N. Fathallah, "Anti-Helicobacter pylori and Anti-Inflammatory Potential of Salvia officinalis Metabolites: In Vitro and In Silico Studies," Metabolites, vol. 13, no. 1, p. 136, 2023.
6. M. Brindisi, C. Bouzidi, L. Frattaruolo, M. R. Loizzo, and R. Tundis, "New Insights into the Antioxidant and Anti-Inflammatory Effects of Italian Salvia officinalis Leaf and Flower Extracts in Lipopolysaccharide and Tumor-Mediated Inflammation Models," Antioxidants, vol. 10, no. 2, p. 311, 2021.
7. P. Triantafyllou, A. Douna, and M. Lambrou, "A Focused Review on Cognitive Improvement by the Genus Salvia L. (Sage) — From Ethnopharmacology to Clinical Evidence," Pharmaceuticals, vol. 16, no. 2, p. 171, 2023.
8. B. Ben Akacha et al., "Sage (Salvia officinalis L.): A botanical marvel with versatile pharmacological properties and sustainable applications in functional foods," Food Bioscience, vol. 59, p. 104193, 2024.
