IMMUNOHISTOCHEMICAL CHARACTERISTICS OF INVASIVE DUCTAL AND LOBULAR CARCINOMAS IN WOMEN FROM THE ARAL SEA REGION

Abstract

Breast cancer remains one of the leading oncological diseases among women worldwide and in the Aral Sea region. Metastatic breast carcinomas represent a clinically and morphologically complex group of malignancies, where tumor aggressiveness and patient prognosis largely depend on biological behavior. While conventional histological methods provide structural information, they are insufficient to fully reveal the molecular characteristics of tumors. Therefore, immunohistochemical (IHC) analysis plays a crucial role in modern oncopathology.